Filter Presets

Filter presets let you save and reuse combinations of filters. VarLens ships with built-in presets for common clinical workflows, and you can create your own.

Preset Bar

The preset bar appears below the toolbar. Click a preset chip to toggle it on or off:

• Active presets are filled with the primary color
• Inactive presets have an outlined border
• Multiple presets can be active at once (their filters combine with AND logic)
• Hover over a preset to see its description

Built-in Presets

These presets ship with VarLens and cover common filtering needs:

Preset	Filter	Use case
Rare Pathogenic	gnomAD AF ≤ 1% + ClinVar Pathogenic/LP	Known rare pathogenic variants
Rare HIGH	gnomAD AF ≤ 1% + Impact HIGH	Rare loss-of-function variants
Rare HIGH+MOD	gnomAD AF ≤ 1% + Impact HIGH or MODERATE	Broader rare impact filter
Ultra Rare HIGH	gnomAD AF ≤ 0.01% + Impact HIGH	Near-absent LoF variants
ClinVar P/LP	ClinVar = Pathogenic or Likely pathogenic	Known pathogenic variants
HIGH Impact	Impact = HIGH	Loss-of-function variants
Rare (1%)	gnomAD AF ≤ 1%	Standard rare variant threshold
CADD >= 20	CADD Phred ≥ 20	Strongly predicted deleterious

Built-in presets cannot be deleted, but you can hide them from the preset bar.

Saving a Preset

When you have filters active, the Save button appears in the preset bar:

1. Click Save
2. Enter a name (required) and description (optional)
3. Click Save — your current filter state is stored as a new preset

Your preset appears in the preset bar and persists across sessions (stored in the database).

Managing Presets

Click the gear icon in the preset bar to open the manage dialog:

From here you can:

• Toggle visibility — hide/show presets in the toolbar bar (eye icon)
• Delete user-created presets (trash icon)
• Built-in presets show a lock icon and cannot be deleted

Using Presets in the Search Bar

You can also activate presets from the DSL search bar by typing @ followed by the preset name:

@rare-pathogenic

The autocomplete dropdown shows available presets when you type @. Preset names are converted to URL-safe slugs (lowercase, spaces to hyphens, special characters removed).